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References
1. Goldring MB. Osteoarthritis and cartilage: the role of cytokines. Curr Rheumatol Rep 2000;2(6):459-65.
2. Towle CA, Hung HH, Bonassar LJ, et al. Detection of interleukin-1 in the cartilage of patients with osteoarthritis: a possible autocrine/paracrine role in pathogenesis. Osteoarthritis Cartilage 1997;5(5):293-300.
3. Towle CA, Trice ME, Ollivierre F, et al. Regulation of cartilage remodeling by IL-1: evidence for autocrine synthesis of IL-1 by chondrocytes. J Rheumatol 1987;14 Spec No:11-3.
4. Ollivierre F, Gubler U, Towle CA, et al. Expression of IL-1 genes in human and bovine chondrocytes: a mechanism for autocrine control of cartilage matrix degradation. Biochem Biophys Res Commun 1986;141(3):904-11.
5. Murata M, Trahan, C, Mankin, HJ, et al. Expression of IL-1 genes in OA cartilage. Trans Orthop Res 2001;26:0674.
6. Fernandes J, Tardif G, Martel-Pelletier J, et al. In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression. Am J Pathol 1999;154(4):1159-69.
7. Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 1998;16(5-6):457-99.
8. Rubartelli A, Cozzolino F, Talio M, et al. A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence. Embo J 1990;9(5):1503-10.
9. Lee RT, Briggs WH, Cheng GC, et al. Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist. J Immunol 1997;159(10):5084-8.
10. MacKenzie A, Wilson HL, Kiss-Toth E, et al. Rapid secretion of interleukin-1beta by microvesicle shedding. Immunity 2001;15(5):825-35.
11. Arend WP, Malyak M, Smith MF, Jr., et al. Binding of IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors in synovial fluids. J Immunol 1994;153(10):4766-74.
12. Eisenberg SP, Evans RJ, Arend WP, et al. Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 1990;343(6256):341-6.
13. Arend WP. Interleukin-1 receptor antagonist: discovery, structure and properties. Prog Growth Factor Res 1990;2(4):193-205.
14. Haskill S, Martin G, Van Le L, et al. cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proc Natl Acad Sci USA 1991;88(9):3681-5.
15. Weissbach L, Tran K, Colquhoun SA, et al. Detection of an interleukin-1 intracellular receptor antagonist mRNA variant. Biochem Biophys Res Commun 1998;244(1):91-5.
16. Muzio M, Polentarutti N, Sironi M, et al. Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist. J Exp Med 1995;182(2):623-8.
17. Butcher C, Steinkasserer A, Tejura S, et al. Comparison of two promoters controlling expression of secreted or intracellular IL-1 receptor antagonist. J Immunol 1994;153(2):701-11.
18. Mankin HJ, Dorfman H, Lippiello L, et al. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg [Am] 1971;53(3):523-37.
19. Saha N, Moldovan F, Tardif G, et al. Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18. Arthritis Rheum 1999;42(8):1577-87.
20. Murata M B, L, Wright, M, Mankin, HJ, et al. Role for IL-1 receptor in the inhibition of proteoglycan synthesis by static mechanical compression. Trans Orthop Res Soc 48th Annual Meeting 2002.
21. Rosette C, Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 1996;274(5290):1194-7.
22. Hofmeister R, Mannel DN, Falk W. Evidence for an intracellular activation loop in the IL-1 system. J Inflamm 1995;47(3):151-63.

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