I am pleased that these additions have been met with enthusiasm on the part of our residents and that the faculty have devoted the time necessary to make these excellent teaching experiences. These additions will continue to strengthen our program over time and provide tremendous opportunity for increasing the residents knowledge of new advances in clinical and basic science.

          One major development in Harvard Orthopaedics has been the Combined Grand Rounds. All of the Harvard Institutions now come together for Grand Rounds. (continued)

Paul Tornetta, MD

Henrik Malchau, MD

Roger Emerson, MD

Mark Mizel, MD

John E. Herzenberg, MD

Peter Trafton, MD

Robert Hotchkiss, MD

Mervyn Letts, MD

Neil Ford Jones, MD

Roland Jacob, MD

M. Timothy Hresko, MD

John E. Lonstein, MD

John Frymoyer, MD

James McAuley, MD

Chitranjan Ranawat, MD

William Harris, MD

John Cuckler, MD

Bjorn Olsen, PhD

Christian Gernber, MD

Dempsey Springfield, MD

Alexander Vaccaro, MD

Josh J. Jacobs, MD

Jon J. P. Warner, MD

James Weinstein, DO

James Urbaniak, MD

Leonard Ruby, MD

Melvin J. Glimcher, MD

Vincent Pellegrini, MD

Daniel J. Berry, MD

Wayne G. Paprosky, MD

Joseph Buckwalter, MD

Henry J. Mankin, MD

Charles H. Brown, MD

Charles Epps, MD

Robin Richards, MD

Evan Flatow, MD

Charles Engh, MD

Wayne M. Sotile, MD

Awards

Valerae O. Lewis, MD

The C. Howard Hatcher Pathology Fellowship for 1999 from the American Orthopaedic Association.

The Award for Best Senior Thesis in Basic Science Research for "PGRB:A Novel Inhibitor of Angiogenesis Detected in Cartilage".

Sigurd Berven, MD

The Award for Best Senior Thesis in Outcomes Research for "A Comparison of Preoperative Disease Severity and Outcome in Patients Undergoing Total Joint Arthroplasty under Two Healthcare Delivery Systems."

Finalist for the New Investigator Research Award given by the British Orthopaedic Research Society for "Expression of BMP-4 in Distraction Osteogenesis: Molecular Mediation of the Stress-Tension Effect."

Martha M. Murray, MD

The 1999 AOA-Zimmer Annual Travel Award for "The Migration of Cells from Human Anterior Cruciate Ligament Explants into Collagen-Glycosaminoglycan Scaffolds in vitro", co-authored with Scott D. Martin, MD and Myron Spector, PhD.

Research Fellowship from the Center for Innovative Minimally Invasive Therapy (CIMIT) for developing intraarticular applications for bioengineered scaffolding material.

David Ring, MD

The 1999 Meyerding Award of the American Fracture Association for "Fracture-Dislocation of the Elbow - The Risk of Recurrent Instability According to Injury Pattern", co-authored with Jesse B. Jupiter, MD and Jeff Zilberfarb, MD.

The 1998 Kilfoyle Award of the New England Orthopaedic Society for "The Functional Outcome of Operative Treatment of Ununited Diaphyseal Fractures of the Humerus in the Elderly", co-authored with Bertrand Perry, MD (former Orthopaedic Hand Fellow at Massachusetts General Hospital), and Jesse B. Jupiter, MD.

The 1997 Kilfoyle Award of the New England Orthopaedic Society for "Monteggia Fractures in Adults", co-authored with Jesse B. Jupiter, MD and N. Sean Simpson (former Orthopaedic Trauma Fellow at Massachusetts General Hospital).

Richard Illgen, MD

The 1996 Kilfoyle Award of the New England Orthopaedic Society for "Femoral Fractures in Children- Treatment with Early Sitting Spica Casting"

Finalist for the New Investigator Research Award given by the Orthopaedic Research Society at the 1999 Meeting for "The Molecular Biology of Fracture Healing: The Role of Osteopontin, the Macrophage, and Vascular Endothelial Growth Factor"

Grants

Richard Illgen, MD

1. OREF Grant for "The molecular biology of osteolysis- An in vitro analysis of a series of clinically relevant osteoclast inhibitors"

2. National Orthopaedic Fellows Foundation Grant for "Assessment of the molecular mechanisms responsible for osteolysis"

Andy Hecht, MD

1. OREF Grant for "The Influence of CBFA1 and Osteocalcin on the Osteotropism of Metastatic Breast Cancer"

2. Susan G. Komen Breast Cancer Foundation Grant with Dr. Peter Haushka for, "Cell Biology of Osteolytic Metastases"

Kevin Bozic, MD

AO North America Resident Research Award for "Use of bioresorbable fixation in hand surgery" Industrial grants for "In vivo evaluation of coralline hydroxyapatite and direct current electrical stimulation in lumbar spinal fusion."

Kingsley Chin, MD

AO North America Resident Research Award for, "Alternative Uses for the Canulated Humeral Blade Plate"

David Ring, MD

AO North America Resident Research Award for, "Elbow Fractures-Long Term Outcome"

Sigurd Berven, MD

Moseley Fellowship for research into the genetic basis of scoliosis in "On the Genetics of Scoliosis and Spinal Deformity"

Cave Fellowship for research on the molecular basis of osteoneogenesis in "Expression of BMP-4 in Distraction Osteogenesis: Molecular Mediation of the Stress-Tension Effect."

Other Achievements

Valerae O. Lewis, MD is coinventor on a pending patent for a novel anti-angiogenesis factor.

Kevin Bozic, MD was accepted to Harvard Business School and will begin studying for his MBA degree January, 2000.

Table 2

          The location varies between Massachusetts General Hospital and The Brigham and Women's Hospital. Many of the talks are teleconferenced to the other site and to the North Shore. In its first year, this Combined Grand Rounds has attracted a set of speakers that represents a veritable who's who of Orthopaedic Surgery. (Table 1) Resident research continues to be an important element of our program.

          Toward that end, we strive to integrate the practice of orthopaedics with new knowledge in clinical and basic science in order to train academic orthopaedists capable of applying new techniques and opportunities in molecular biology to problems of the musculoskeletal system. It is this knowledge, applied in new ways that has the potential for yielding innovations and breakthroughs in the treatment of common, disabling conditions that comprise orthopaedic medicine. Resident researchers have compiled an impressive list of awards, grants, and other accomplishments. (Table 2) The group of residents that will graduate next month have been an outstanding group of young physicians.

 They have shown extraordinary commitment to education and patient care. Harvard graduates continue to have their pick of the best fellowships and private practice jobs as evidences by the plans of the current graduating class. (Table 3) We look forward to welcoming a new group residents in July.

         In my role as Chairman of the Partners Department of Orthopaedic Surgery, bridging the Departments of Orthopaedic Surgery at the Massachusetts General and Brigham and Women's Hospitals, I would like to share with you several initiatives that will contribute to the residency program in the coming years.I am particularly pleased with the addition of several key faculty members who will benefit both the clinical and research elements of the program. In the spring of last year, I recruited Harry Rubash to head orthopaedics at the MGH and Jon J.P. Warner to head the Department's Shoulder Service.

.Harry's proven leadership ability, coupled with his clinical expertise in arthroplasty and innovative research interests, will contribute greatly to the growth and continued excellence of the MGH program. As Chief of the Shoulder Service, J.P. is developing a practice that spans the BWH and MGH Partners Department, including the BWH's new Sports Medicine and Rehabilitation Center. A third key Partners recruitment, arriving May 1999, is Mark Vrahas. Mark is a nationally recognized trauma surgeon who will serve as Chief of Orthopaedic Trauma Services for Partners Orthopaedics. Mark will play a critical role in the training of our chief residents at both the BWH and MGH in the area of trauma.

          An initiative aimed at strengthening research capability across Harvard Orthopaedics is the development of a "Center for Molecular Orthopaedics" based in the Partners Department of Orthopaedics. (continued)