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Use of the LISS for Distal Femur and Proximal Tibia Fractures: Current Practices and Ongoing Research Robert O'Toole MD, Raymond Hwang, Malcolm Smith MD, Mark Vrahas MD
DEPARTMENT OF ORTHOPAEDICS, MASSACHUSETTS GENERAL HOSPITAL, BOSTON MA

Introduction

The surgical treatment of distal femur and proximal tibia fractures has presented significant challenges, particularly in elderly osteoporotic patients. Varus and valgus malalignment, implant failure, joint stiffness, infection, non-union and technical difficulty have all been associated with previous treatment techniques1. The LISS (Less Invasive Stabilization System, Synthes USA, Paoli, PA) was developed to address these issues for a subset of periarticular fractures about the knee2. We have begun to utilize this system at our institutions and are beginning to evaluate its efficacy for this class of difficult fractures.

Background

LISS plates differ significantly from more traditional plating systems that have been used for these fractures. The fundamental difference is that all of the screws in a LISS plate are “locking” screws. The threaded screw head locks into the plate and can only be inserted at one angle. The angle between the plate and screw is therefore fixed in space, allowing each individual screw to function as a mini blade plate. The LISS can be thought of as analogous to an external fixator that is beneath the skin.

Since each screw in the LISS is fixed to the plate, there is no need for the plate to touch the bone, thus reducing the disruption to the bone's blood supply by decreasing the plate's footprint. Additionally, the plate can be inserted with a percutaneous technique, minimizing the disruption to the fracture's soft tissue envelope3. Furthermore, the plate's locking screw construct, like other locking plates, changes the failure mechanics of the plate. It is theorized that unlike traditional plates --which can fail one screw at a time-- the locked nature of the LISS plate screws requires that the plate fail by all of the screws pulling out together. This failure mode provides added structural support that is thought to be particularly important in osteoporotic bone4,5.

Indications

The LISS plate has been used at our institution for four clinical situations:

  1. Proximal Tibia Fractures (AO Types A2,3 and C1,2,3)
  2. Distal Femur Fractures (AO Types A1,2,3 and C1,2,3)
  3. Non-unions and delayed-unions of the above fractures.
  4. Periprosthetic fractures of the distal femur associated with TKR or hip arthroplasty.

AO Type A fractures in this study group are periarticular fractures that do not cross the articular surface6. Type C fractures are "complete" articular fractures that involve the articular surface and also have a fracture line that completely separates the articular surface from the diaphysis.

When feasible, the plate is inserted using a percutaneous technique7. If the reduction cannot be achieved adequately with the percutaneous approach, a more traditional extensile approach can be used. An external guide allows all of the screws to be placed percutaneously, without need for fluoroscopic guidance. The screws are self-tapping, self-drilling, and typically unicortical, further facilitating the ease of application of the system.

Methods

The LISS began use at the Massachusetts General (MGH) and Brigham and Women's (BWH) hospitals in July of 2001 by the Harvard Orthopaedic Trauma team under the direction of Drs. Mark Vrahas and Malcolm Smith. In addition to its use on the trauma service, the system has also been used on the arthroplasty services for treating periprosthetic fractures.

The current study, with IRB approval, has tracked all of the cases where the LISS plate was used from July 2001 until September of 2002. The cases were found by utilizing Ortho DUDE, the trauma database developed by the Harvard Combined Orthopaedic Residency Program8, and by reviewing all of the operative notes for CPT codes from fractures appropriate for the LISS. Analysis has involved review of operative notes, computer records, and radiographs.

Results

During the first 15 months of its use we identified 94 cases where the LISS was used at the MGH and BWH. These cases have undergone preliminary analysis. Thirty-nine percent of cases were for femur fractures and 61% for tibia fractures. Twelve of the femur fractures (32%) were associated with either a total knee or hip arthroplasty. The average age for the periprosthetic fractures was 82 years. The average age of the patients was 56 years old (range of 20 to 93). The most common injury mechanisms were a fall from standing (45%) and motor vehicle collisions (21%).

The initial operative experiences have yielded encouraging results. Anecdotally, patients have appeared to tolerate weight bearing more quickly than with prior techniques, although this requires further research to verify. Longer term analysis of clinical and radiographic union rates, complications, and outcomes is ongoing at the time of this writing. There are few reports in the literature detailing outcomes with this technique, and we hope that our study will add significantly to our knowledge of this surgical technique.

Conclusions

Periarticular fractures at the knee present difficulties, particularly in the osteopenic patient or the patient with a preexisting prosthesis. The LISS has been proposed as a tool with significant promise for improving the care of these fractures. Our initial experiences with the first 94 patients at our institutions have been encouraging, and these patients form a data pool to begin more rigorous evaluation of the merits of this technology. The initial experience with LISS appears to be fueling its use, as at least 50 more cases have been performed in the 5 months after the study period.

Our newly developed database, Ortho DUDE, is assisting in the trauma service's ability to better analyze outcomes, and this project is one of many that are likely to emerge in the future as the trauma database facilitates outcomes studies.

Acknowledgements

Ms. Suzanne Morrison continues to make significant contributions to this work. Additionally we wish to thank the radiology technical staff at MGH and BWH for their assistance in this project.

Notes:

Dr. Robert O'Toole is a Resident, Harvard Combined Orthopaedic Residency Program, Boston, MA.

Mr. Raymond Hwang is a medical student, Harvard Medical School, Boston, MA.

Dr. R. Malcolm Smith is an Attending Physician, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA.

Dr. Mark Vrahas is Attending Physician and Partners Chief of Orthopaedic Trauma Services, Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA.

Please address correspondence to:
Dr. Robert O'Toole
C/o Harvard Combined Orthopaedic Residency Program
55 Fruit Street, GRB-622
Massachusetts General Hospital
Boston, MA 02115
617-726-2942
rotoole@partners.org

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