MASSACHUSETTS GENERAL HOSPITAL
Harry E. Rubash, MD
CHIEF OF ORTHOPAEDIC SURGERY, MASSACHUSETTS GENERAL HOSPITAL
EDITH M. ASHLEY PROFESSOR OF ORTHOPAEDIC SURGERY, HARVARD MEDICAL SCHOOL






Introduction

As I write my 12th Annual Chief's Report to the Orthopaedic Journal at the Harvard Medical School, the financial markets appear to have stabilized, and we remain in a deep recession. On March 23, 2010 our 44th President signed his comprehensive health care reform bill, the Patient Protection and Affordable Care Act, into law. This new law requires most U.S. Citizens and legal residents to have health care insurance and creates a state-based American Health Benefit Exchange System through which individuals can purchase coverage. This is not dissimilar to the Exchanges available in the Massachusetts Health Care Program. In addition, this new bill expands Medicare to many individuals under the age of 65 and provides a series of premium and cost-sharing subsidies to individuals of need.



In addition, there are significant tax changes related to the new health insurance program with an increased tax-rate on wages and excise tax on insurers and medical devices. The impact of these tax changes will have enormous repercussions upon our profession. There are also changes to the private insurance sector with the establishment of the temporary national high-risk pool and new insurance market pools. There are a series of measures designed to improve the quality of our health care system as well as the health-system's performance. The field of comparative-effectiveness research will receive an enormous boost as a result of a series of patient-centered outcomes research institutes, demonstration projects, and national Medicare Pilot Programs. We were fortunate to have heard about one of these programs at Grand Rounds on May 20, 2010 when Richard White, MD, Medical Director, New Mexico Center for Joint Replacement Surgery, in Albuquerque, New Mexico, presented a talk entitled, "Potential Advantages and Dangers for Orthopaedic Surgeons with Participation in A Bundled-Payment Model." It was a sobering and insightful presentation. A new national prevention, health care promotion, and public health council will coordinate federal prevention, wellness and public health awareness activities. Long-term care will also be affected with the establishment of a national voluntary insurance program for community living assisted services. As we all know, the implementation of the new taxes will precede the actual benefits of the program and thus an enormous number of challenges and modifications will occur.

I have spent many hours reviewing the details of this bill and find it to be very perplexing. Yet, I remain hopeful that we will be able to continue to deliver our high-quality patient care at all of our hospitals and outpatient programs throughout the country. I eagerly await the analysis of the implications of this bill as it transitions our care. I am also concerned that millions of Americans are being steered into a program that has consistently under-performed for our patients and providers. Presumably, the best is yet to come and we have an obligation to be involved in the discussion. The midterm elections should bring some clarity.

IN MEMORIAM

In April we were saddened by the passing of Ms. Linda Honeycutt of the Orthopaedic Trauma Service. Ms. Honeycutt was a long-time employee of the MGH and an integral part of the Department of Orthopaedic Surgery. She worked most recently as assistant to Mark Vrahas, MD, Chief of Partners Orthopaedic Trauma. I first met Ms. Honeycutt over 20 years ago during my Arthroplasty Fellowship at the MGH.

Ms. Honeycutt's outgoing personality, infectious laughter and unmistakable Southern drawl could make anyone feel welcome and at home. She would often stop by my office with fresh tomatoes and blueberries from Wilson's Farm, her favorite local farm stand.

In May the Department hosted a memorial service in celebration of Ms. Honeycutt's life. The standing room only event in the MGH Chapel was filled with words of remembrance and shared memories.

Ms. Honeycutt will be terribly missed.

FACILITIES

Building of the 3rd Century

We are eagerly anticipating the opening of the Building of the 3rd Century which is expected to open to patients in the summer of 2011. For the last two years we have been watching this massive structure take shape at the site of the former Vincent and Clinics Buildings. The opening in 2011 coincides with the 200th anniversary of the MGH. This facility will occupy nearly a half million square feet and will be the home to Radiation Oncology, Radiology, In-Patient and Out-Patient Surgery, and twelve new Operating Rooms and will include increased Intensive Care capacity. We also plan to have an "Orthopaedic Surgery Operating Room of the Future" with the most-advanced navigation and robotic equipment available. The top five-floors of this massive complex will provide space for increased bed capacity for Cancer, Neurology and Neurosurgery. With the completion of the Building of the 3rd Century, patients, visitors, and staff will be able to navigate through the main campus with new and more direct pedestrian routes including connections which will eliminate the need to go outdoors to travel from the "front" of the main campus to the "back."

Another exciting aspect of the Building of the 3rd Century is a new Emergency Department which will be located in the White Building on the Lobby level. Mr. Sumner Redstone, Executive Chairman of the Board of Directors of Viacom pledged over $40 million to develop the new Emergency Department which will offer advanced state-of-the-art care.

The Building of the 3rd Century will undoubtedly be the crowning jewel on the MGH main campus. We eagerly await its completion and our fabulous new operating rooms. Mark Vrahas, MD, Chief of Partners Trauma, will be the Orthopaedic "Czar" of the new OR facility and our representative in the MGH OR Administration. Dr. Vrahas and Thomas Holovacs, MD, Director of the Outpatient Operating Rooms will work closely in the new OR facility.

Brigham and Women's / Mass General Heath Care Center at Foxborough

The Brigham and Women's/Mass General Health Care Center at Foxborough has been open now for over a year and continues to provide outstanding care to patients South of Boston. Located at Patriot Place, it is a 1.3 million square foot development adjacent to Gillette Stadium. This modern 93,000 square foot, four-story Center houses physician offices, four operating rooms for outpatient surgery, and advanced diagnostic imaging. Primary Care Services are available at the Center as well as Orthopaedic Surgery and other specialty services including: Cardiology, Dermatology, General and Gastrointestinal Surgery, Pain Management, Plastic Surgery, Rehabilitation and Sports Medicine.

The growing list of physicians seeing patients at this facility includes Thomas Gill, IV, MD; Andreas Gomoll, MD; Peter Ansis, MD; Eric Berkson, MD; Richard de Asla, MD; Thomas Holovacs, MD; Chaitanya Mudgal, MD; Joseph Schwab, MD; Philip Blazer, MD; Christopher Bono, MD; Christopher Chiodo, MD; Wolfgang Fitz, MD; and Scott Martin, MD. We are pleased to have recently added Pediatric Orthopaedics to the medical services offered and we welcome Gleeson Rebello, MD to the staff.

Congratulations to Dr. Berkson, who was recently named as the new Medical Director at the Center for the MGH physicians. Dr. Berkson will follow in the foot steps of Dr. Gill, our first Medical Director.

The Brigham and Women's / Mass General Health Care Center is a fine addition to our Department and we look forward to providing specialized care and convenience to our patients in the Foxborough area. This Center is an important element of the Patriot Place complex which includes shopping, restaurants, and entertainment. Our future offerings there will include a Performance Analysis Center under the direction of Dr. Berkson and a Center for the Early Detection and Treatment of Hip and Knee Arthritis.

Stephan L. Harris Chordoma Center

This year we were extremely pleased to open The Stephan L. Harris Center for Chordoma Care at the MGH. Under the direction of Francis Hornicek, MD, PhD, the Center offers patients access to a multidisciplinary group of physicians and clinicians who specialize in the diagnosis and the treatment of chordomas. Our team of clinicians: Francis Hornicek, MD, PhD; Frank Pedlow, MD; Kevin Raskin, MD; Joseph Schwab, MD; and Dempsey Springfield, MD, represent one of the largest chordoma treatment groups in the country. This is the first center in the world with a single focus on chordoma care. The Center includes Orthopaedic Oncologists and Orthopaedic Spine Surgeons, as well as dedicated nursing, and is staffed by radiation and medical oncologists, neurosurgeons, plastic surgeons, radiologists, pathologists, ENT’s and researchers. Chordoma is a rare malignant bone tumor; the treatment is complex and can be difficult. In a recent study, the Harris Center clinicians achieved a five-year continuous disease-free survival rate of 62.5% with primary sacral chordoma. The Stephan L. Harris Center is a center of excellence at the MGH that provides unsurpassed compassionate care while advancing the art and science of evaluating, diagnosing, treating, curing, and supporting the patient with chordoma.

Congratulations to Dr. Hornicek and his team for this amazing Center!

The Jim & Ellen Kaplan Center for Joint Reconstruction Surgery at Newton Wellesley Hospital

The Jim & Ellen Kaplan Center for Joint Reconstruction Surgery at Newton-Wellesley Hospital (NWH) continues to flourish under the leadership of Director, Joseph McCarthy, MD. Dr. McCarthy, Vice-Chairman of the MGH Department of Orthopaedic Surgery, is joined at the NWH by new faculty members Hany Bedair, MD and John Kwon MD. Dr. Bedair joined the Department in 2009 and Dr. Kwon will be joining us later this summer. We continue to expand this important relationship with the fantastic physicians at the NWH.

FACULTY UPDATES

The Department and the Adult Reconstructive Surgery Service were pleased to welcome two new members in 2009, Hany Bedair, MD and Young-Min Kwon, MD, PhD.


Dr. Bedair graduated from Yale University School of Medicine and did his residency at the University of Pittsburgh Medical Center. He joined the Department after completing an Orthopaedic Adult Reconstruction Fellowship at Rush University Medical Center. Over the last year, Dr. Bedair has been working closely with Dr. Andrew Freiberg and Dr. Joseph McCarthy at the Jim & Ellen Kaplan Center for Joint Reconstruction Surgery. Dr. Bedair’s clinical interests are in the area of adult reconstructive surgery of the hip and knee (total hip, total knee arthroplasty, partial knee arthroplasty), including complex primary and revision surgery and his research interests focus on periprosthetic infections, arthrofibrosis, and clinical outcomes.


The Knee Society recently honored Dr. Bedair with the Mark Coventry Award. This national award was presented to Dr. Bedair for his research on detecting infections earlier in joint replacement patient. Congratulations Dr. Bedair on this wonderful achievement!

Dr. Bedair recently joined the leadership of the Harvard Medical School Annual Advances in Arthroplasty Course. He is working closely with myself and Dr. Andrew Freiberg on the program content. We look forward to Dr. Bedair's impact on our Department.

It was also a pleasure to welcome back to the Department and the Adult Reconstructive Surgery Service, Young-Min Kwon, MD, PhD. Dr. Kwon was a Fellow in our Adult Reconstructive Surgery Service from 2005-2006. Dr. Kwon joined the Department last fall after finishing his PhD in the Nuffield Department of Orthopaedic Surgery at the University of Oxford. Dr. Kwon graduated with his medical degree from the University of Sydney in Australia. He followed with a hip and knee fellowship here at the MGH and then completed a second hip fellowship at the University Hospital Balgrist, Zurich, Switzerland. Dr. Kwon has qualified as a specialist in Orthopaedic Surgery in both the Royal College of Surgeons of England and the Royal Australian College of Surgeons. Dr. Kwon’s expertise in metal-on-metal hip replacements is recognized with numerous awards, including the New Investigator Award from Orthopaedic Research Society (ORS) for his research. Dr. Kwon is dividing his time between his clinical activities and research in the Harris Orthopaedic Laboratories (HOL). Dr. Kwon has recently joined the leadership of the Harvard Medical School Annual Advances in Arthroplasty Course and he has also assumed the role of Director of our outstanding Adult Reconstructive Surgery Fellowship Program.


Welcome to Dr. Kwon and his wife, Emma and their two sons, Oh-Jak aged 3 years, and Oh-Joon aged 3 months to the MGH community. I look forward to Dr. Kwon's many continued contributions to the Department and the field.


It was a distinct pleasure to have welcomed Luke Oh, MD, last year to the Department as the newest member of the Sports Medicine Service and the Shoulder Service. Since starting his practice here at the MGH in October 2009, Dr. Oh has had many noteworthy accomplishments. He was the Recipient of the 2010 Mel Post Award for Excellence in Clinical Research from the American Shoulder and Elbow Surgeons. He received a Department AEF Grant to study, "The In-Vivo Kinematics of the Shoulder After a Latarjet Procedure." Dr. Oh became the Elbow Consultant for the Boston Red Sox and the Team Physician for the New England Revolution. He is an active member of the Department and the Coordinator of the weekly Sports Medicine Conference, the Sports Medicine Indications Conference, and the monthly Sports Medicine Journal Club.



Congratulations Dr. Oh on these fine accomplishments!

I am pleased to introduce Adam Hacking, PhD, to the Department. Dr. Hacking joined our Department last spring and is the Director of the newly created Laboratory for Musculoskeletal Research and Innovation (LMRI). Dr. Hacking has broad research interests related to improving orthopedic treatment and patient care and his laboratory is focusing on providing innovative solutions for unmet clinical needs in orthopedics.

Dr. Hacking received his PhD in Biomedical Engineering Dr. Young-Min Kwon 34 from McGill University in 2006. During this time, Dr. Hacking was the recipient of the Hip Society’s prestigious Otto Aufranc Award in 2002 for his PhD work implicating the role of the surface morphology of plasma sprayed HA coatings in osseointegration. While working on his PhD, Dr. Hacking co-authored a number of pre-clinical studies validating and optimizing the properties of Trabecular Metal for hard and soft tissue fixation. Dr. Hacking completed two post doctoral fellowships, the first in the Department of Orthopaedics at McGill University and the second with Dr. Ali Khademhosseini at the Harvard-MIT Division of Health Sciences and Technology. He has authored 4 book chapters, 28 journal publications, generated 4 patents, presented more than 50 conference talks and has delivered numerous invited lectures.

Welcome Dr. Hacking to the Department. We eagerly await your contributions to our research mission.

In August we welcomed John Y. Kwon, MD, to the Department and the Foot and Ankle Service. Dr. Kwon received his medical degree from New York Medical College in Valhalla, NY with AOA honors and distinction. He was a surgical intern at the MGH and an orthopaedic resident in the Harvard Combined Orthopaedic Residency Program from 2005-2009. He went on to complete an outstanding Foot & Ankle Surgery Fellowship at the Institute for Foot and Ankle Reconstruction at Mercy Medical Center in Baltimore, MD under the guidance of director, Mark S. Myerson, MD. Dr. Kwon then went on to complete additional training in Portland, Oregon under the tutelage of Doug Beaman, MD, on the use of the Taylor Spatial Frame for foot & ankle and trauma applications.

Dr. Kwon has a keen interest in various foot and ankle problems including trauma, post-traumatic deformity correction, flat foot reconstruction, tendon injuries and arthritis. In addition, he has a strong interest in translational and basic science research and will be an anchor in our newly developed Foot and Ankle Laboratory. Dr. Kwon is dividing his time between the MGH, Newton Wellesley Hospital and the laboratory.

Dr. Kwon, welcome to the Department!

SERVICE UPDATES

Arthroplasty (Adult Reconstructive Surgery) Service

The Arthroplasty Service under the direction of Service Chief and Department Vice Chair, Andrew Freiberg, MD, continues to grow and prosper not only on the main campus but also at the Newton Wellesley Hospital (NWH). Once again the Arthroplasty Service had an outstanding presence at this year’s Orthopaedic Research Society, The Knee Society, The Hip Society, and the American Association of Orthopaedic Surgeons Annual Meetings in New Orleans, LA with 15 podium presentations, posters, and exhibits. Henrik Malchau, MD, PhD, and co-investigators had the distinct honor of receiving the very prestigious Sir John Charnley Award from the Hip Society for innovative research on surgical technique and acetabular component position. Hany Bedair, MD, won the Knee Society Award for his work on diagnosis of infection in total knee replacements. We were also well represented by our clinicians and researchers at the American Academy of Hip and Knee Surgeons Annual Meeting in Dallas, TX this year.

Our clinical practices continue to grow and Young Min Kwon, MD, PhD has been a fine addition to our Service. Dr. Kwon’s special interest in hard bearing surfaces and their failure mechanisms is a fine compliment to the group both clinically and in the research arena.

The entire Arthroplasty Service has worked hard with various initiatives to improve peri-operative efficiency, safety, and opportunity for improved volume. Our clinical volume has grown to 1600 procedures at MGH and approximately 600 at NWH. Both of the Arthroplasty Programs, MGH and NWH, were selected by Blue Cross/Blue Shield as Centers of Distinction for Hip and Knee Arthroplasty Excellence. The Kaplan Center at the NWH is gaining regional recognition for outstanding patient satisfaction and outcomes. Well Done!

Close collaboration continues between members of the Arthroplasty Service and the Bioengineering Laboratory, under the direction of Guoan Li, PhD. Dr. Li reports, "We continue to work on a better understanding of gender differences in kinematics, patello-femoral issues and biology of the knee." Our Fellows continue to work with Dr. Li and his outstanding graduate students and report great success in their research experience. In collaboration with the Harris Orthopaedic Laboratories, we continue to enroll patients in clinical studies of Vitamin E highly cross-linked polyethylene.

This year marks our 50th Fellowship class! This year’s Fellows were another exceptional group: Jennifer Peter, MD; Anthony Marchie, MD; Matthew Beal, MD; and Philip Glassner, MD. We wish them much success as they begin their careers. Dr. Peter has joined one of our previous Fellows, William Allen McGann (Class of 1984) in practice in San Francisco, CA. Dr. Marchie joined a practice in Toronto, Canada. Dr Beal joined Ohio State Univeristy in an academic practice and Dr. Glassner has joined his family in practice in NJ. Best wishes to our Fellows on all their future endeavors!

Preparations are currently underway for our Harvard Annual Advances in Arthroplasty Course: Burning Issues and The Young Adult With Hip Disease From Early Detection to Arthroplasty. The Course will take place September 28-October 1, 2010 at the Hyatt Regency Hotel in Cambridge. This year marks the 40th presentation of the course, making it the longest Continuing Education Course at Harvard Medical School. In order to celebrate this significant milestone, the format of this year’s program will be new and innovative, highlighting today's important challenges in the field of total joint arthroplasty. Our Keynote speaker for "The Annual Harris Oration" will be Clive Duncan, MD, FRCS(S) who will be presenting a talk entitled, "Just a Thought But See it Through." For more detailed information, or to obtain a registration form, contact Harvard Medical School, Department of Continuing Medical Education at (617) 384- 8600 or e-mail: hms-cme@hms.harvard. edu . Visit them on the web at http://cme.med.harvard.edu/.

Podiatry Service

The MGH Podiatry Service under the direction of Service Chief, Robert Scardina, DPM, provides ambulatory foot care, out-patient surgery, orthotic services, and non-invasive lower extremity arterial testing in the Yawkey Building. Other practice sites include: Revere, Chelsea and Charlestown Health Centers, the South End Community Health Center and the Lynn Community Health Center. There are nine professional staff members in the group. The Podiatry Service staff includes a full-time orthotic technician, Nancy Ferullo as well as Medical Assistant and Front End support staff. The Podiatry professional staff provides in-patient consultation services at the MGH and Spaulding Rehabilitation Hospital. The Podiatry Service maintains a valuable clinical relationship with the MGH Orthopaedic Foot and Ankle Service and will soon develop a more formal collaboration.

The MGH Podiatry Residency Program has one of the most comprehensive curricula in the country, including over twenty non-Podiatry medical and surgical month rotations, broad and diverse longitudinal training experiences in clinical podiatry and foot and ankle surgery, and extensive didactic activities. The residents receive training in foot and ankle surgery from over twenty-five faculty members – podiatric, orthopaedic and plastic surgeons.

The Seventh Annual MGH Podiatry Service Winter Lecture, 'Forensic Podiatry' with guest speaker: David Agoada, DPM, Harvard Vanguard Medical Associates was held in January. Attendees included podiatrists, podiatric MAs, and medical professionals from MGH and other metropolitan Boston hospitals.

Dr. Scardina notes:

"Each member of our Service is dedicated to excellence in patient care and post-graduate education. Expanding our clinical practice within existing locations and to new Partners facilities is a necessity and a priority for us. Our newly recruited staff member's background should facilitate development of a 'research arm' for our Service - yet another objective we hope to achieve in the near future."

Hand and Upper Extremity Service

The Hand and Upper Extremity Service continues to expand both in clinical volume, teaching programs, and clinical and basic research. The flexibility of our entire faculty has allowed the Hand Service to maintain its very high standard of clinical and academic output and excellence.

In March of this year, Jesse Jupiter, MD, stepped down from his position as Chief of the Hand and Upper Extremity Service. Chaitanya Mudgal, MD, was asked to assume the position of Interim Chief of the Service. A national search is currently underway through Harvard Medical School for a new Chief of the MGH Hand and Upper Extremity Service.

Jesse Jupiter, MD, Chaitanya Mudgal, MD, David Ring, MD, PhD, and Sang-Gil Lee, MD, have been very busy utilizing the excellent outpatient surgery facilities at MassGeneral West. Drs. Jupiter and Mudgal also regularly see patients at the MassGeneral West. Outreach efforts have further lead to Dr. Mudgal seeing patients as well as operating at The Brigham and Women's/Mass General Health Care Center at Foxborough. These outreach efforts have lead to very valuable collaborative efforts at providing comprehensive patient care to patients located far from the Metro Boston area.

Organizationally, the Hand and Upper Extremity Service has undergone substantial re-structuring over the last year. This was largely the result of our efforts to improve office efficiency and to improve the level of access and expeditiousness of access for our patients. We invited a consultant to observe and advise in this plan. Additionally, Dr. Mudgal and Mr. David Gaynor conducted a site visit to a similar facility in Philadelphia. The overall result was a better re-structuring of office personnel, the telephone system as well as an increased emphasis on our mission statement of having a Hand Surgeon see each new patient presented to the offices. Expanding our service perimeter to Waltham and Foxborough has further enhanced the Service's efficiency.

The Hand Surgery Fellowship is now in its third year as a combined fellowship with the Plastic Surgery Service. Dr. Mudgal has completed his first year as the Program Director. Jonathan Winograd, MD, and Curtis Cetrulo, MD, from Plastic Surgery have added to the fellow’s education with their expertise in free tissue transfers as well as management of brachial plexus injuries. The Service continues to enhance educational and academic content regularly, with updates to the ‘Hand CD'. The fellows now have regular access to microsurgical lab facilities under the supervision of Mr. Mark Randolph from the Plastic Surgery Service. We are pleased with the continued collaboration of the Hand Service and Plastic Surgery as it further enhances the fellow's experience and education during their time at the MGH. This year also saw the beginning of a new elective cross rotation with a Hand Fellow from the Beth Israel Deaconess Medical Center (BIDMC). This promises to be an exciting new addition to our program. The Service’s Journal Club has been firmly established as a collective effort across the BWH as well as the BIDMC. Journal Club meetings rotate among the three facilities and are extremely well attended by fellows, faculty, researchers, residents as well as by hand therapists. Reports indicate that the collegial spirit in which these meetings are conducted and the knowledge exchanged has made them an invaluable source of education for all.

The Service continues to have PhD candidates doing research under the guidance of Dr. Ring, and last year Anneluuk Lindenhovius successfully completed her PhD. John Sebastiann Souer completed the research work on his PhD and will be defending his dissertation in the near future. The Service continues also to regularly host several short-term research associates, who enhance our research efforts and productivity. The Service continues to have a steady stream of international visitors for varying periods of time during the academic year. We are happy to have the AO fellows visit regularly for 3 months.

Academic productivity continues to remain high. The Hand and Upper Extremity Service has nearly two dozen peer-reviewed publications and has also produced over twenty clinical communications and review papers and nearly a dozen book chapters. The faculty continues to be regularly featured in local, regional, national, and international symposia with roles varying from speakers to moderators to course chairmen. Two of our MGH hand therapists Colleen Lowe and Carol Mahony participated as faculty in Instructional Courses at the Annual Meeting of the American Society for Surgery of the Hand.

Shoulder Service

The Harvard Shoulder Service, under the direction of Service Chief, Jon J.P. Warner, MD, has continued in its mission to lead in clinical service, teaching, and research. The Clinical volume continues to grow through the busy practices of Thomas Holovacs, MD, and Jon J.P. Warner, MD, with over 1000 shoulder surgeries performed this past year. Dr. Warner reports, "The addition of Luke Oh, MD, has been a wonderful enhancement to the Harvard Shoulder Service as he brings not only an expertise in the management of shoulder problems but advanced treatment methods for management of elbow problems." Dr. Oh joined the Department after a one year fellowship program in Shoulder and Elbow at the Mayo Clinic. Prior to this he was a Sports Medicine Fellow at the MGH and he has a duel appointment on the Harvard Shoulder Service and the MGH Sports Medicine Service.

Another notable accomplishment this year was the election of Dr. Warner to the Presidential Line of the A.S.E.S. (American Shoulder and Elbow Surgeons). This year the Harvard Shoulder Service also had two of its research papers nominated for the prestigious Neer Award of the A.S.E.S.

The four Shoulder Fellows are making their final plans for their first year in practice. Anup Shah, MD, will go into private practice in Sports Medicine and Shoulder in Atlanta, GA. Danny Goel, MD, is considering a number of academic opportunities from Vancouver to Philadelphia. James Romanowski, MD, will practice either in the Cincinnati area or in the Charlotte, NC area, and Bryan Butler, MD, is contemplating an academic position in Shoulder and Sports Medicine either in Baltimore or Columbus, Ohio.

Orthopaedic Oncology Service

The Orthopaedic Oncology Service under the direction of Service Chief, Francis Hornicek, MD, PhD, is one of the largest in the world. Members of the Orthopaedic Oncology Service have been pioneers in the area of transplantation in limb sparing procedures and in complex pelvic and spine surgery for malignant bone and soft tissue tumors.

The Orthopaedic Oncology, Medical Oncology, Radiation Oncology Services and the members of Pathology and Radiology from the Center of Sarcoma and Connective Tissue Oncology, part of the MGH Cancer Center, provide comprehensive care for patients with bone and soft tissue tumors which are benign and malignant in children and adults. They are a regional, national and international referral center for these complex tumors. Kevin Raskin, MD; Dempsey Springfield, MD; Joseph Schwab, MD; and Dr. Hornicek continue to divide their clinical service with additional passions including orthopaedic research and medical student and resident education. Dr. Hornicek and Zhenfeng Duan, MD, PhD, run the Molecular Sarcoma Laboratory and have ongoing multiple collaborative efforts to study tumor agenesis and stem-cell research on tumor pathogenesis.

The Musculoskeletal Tumor Fellowship, one of the most sought after in the country, brings together members of Beth Israel Deaconess, The Children’s Hospital and the MGH to develop an undisputed world-class Fellowship program. The Orthopaedic Oncology group has a truly impressive past, a highly productive present and a future that includes innovation in many areas!

Henry J. Mankin Professorship in Orthopaedics

Henry Mankin, MD, was Chief of the Department of Orthopaedic Surgery from 1972-1996 and was also Chief of the Orthopaedic Oncology Service. He is a worldrenowned leader in orthopaedic oncology, cartilage research and bone transplantation for tumors. The Henry J. Mankin Professorship in Orthopaedics is a fitting tribute to his many contributions to the field of Orthopaedic Oncology.

In his distinguished career, which spans over 50 years, Dr. Mankin has cared for patients with tumors and metabolic bone diseases and conducted innovative research on biologic, oncologic, and metabolic issues.

Dr. Mankin has been recognized for the leadership roles he has held throughout his career, including Chief of Orthopaedic Surgery at the MGH and President of the Orthopaedic Research Society, the American Orthopaedic Association, and the American Board of Orthopaedic Surgeons. I and many others at the MGH believe that his dedication to the health and wellbeing of others merits a further distinction - a Professorship named for him at Harvard Medical School.

By establishing the Dr. Henry J. Mankin Professorship in Orthopaedics, we will honor Dr. Mankin's legacy in perpetuity - ensuring that generations of young surgeons will be taught by clinician-scientists who exemplify his intellect, energy and empathy. Therefore, I hope you will join with me, colleagues in the department, and Dr. Mankin's former students and patients in making a gift to establish this endowed professorship. You will be pleased to know that we have already received gifts and pledges totaling $1.1 million toward our goal of $3.3 million. To make your tax-deductible gift, or if you would like information on other ways to give, please contact Bob O'Brien in MGH's Development Office at 617-726-0991 or rhobrien@ partners.org. Thank you!!!

Pediatric Orthopaedic Service

The Pediatric Orthopedic Service under the direction of Service Chief, Brian Grottkau, MD, continues its work to help our youngest patients. During Fiscal Year 09 members of the Service, Dr. Grottkau; Saechin Kim, MD; and Gleeson Rebello, MD, saw nearly 8500 patients. Dr. Rebello who focuses on afflictions of the pediatric, adolescent and young adult hip is now seeing patients weekly at the Brigham and Women's/ Mass General Heath Care Center at Foxborough. Drs. Kim and Grottkau are each seeing patients on a weekly basis at the North Shore Center for Outpatient Care in Danvers. Plans are underway to hire a Nurse Practitioner to aid the Service in the Foxborough and Danvers sites. Dr. Grottakua reports, "Our patients’ families have been quite pleased with the relaxed, efficient atmosphere and the high quality of care received."

Members of the Service are also pleased to continue the research program within the Laboratory for Tissue Engineering. Yunfeng Lin, DMD, PhD, joined the Laboratory as a post-doctoral fellow last year. Research continues to move along at a brisk pace. Members of the Laboratory are working on many interesting topics involving adipose derived stem cells with the ultimate goal of developing novel therapeutic applications for pediatric orthopedic and spine afflictions.

Sports Medicine Service

The Sports Medicine Service under the direction of Service Chief, Thomas Gill, IV, MD, continues to see exponential growth in terms of staff and of programs.

A major development in the Sports Medicine Service has been the establishment of several programs in the Brigham and Women's/Mass General Heath Care Center at Foxborough. Eric Berkson, MD, Luke Oh, MD and Kelly McInnis, DO, have the major parts of their practices there, and Dr. Berkson has recently been named the Medical Director of the Foxborough Center. A major Performance Center for the evaluation of athletes at all levels of activity has opened in the Sports Medicine Service. The main focus will be the evaluation, study, and performance improvement of the baseball throwing motion and the golf swing. The Foxborough site is also the trial site for the development of a Sports Medicine database which began on July 1, 2010. A program to inform the local communities of the facilities that the Service has to offer in Foxborough has started.

The medical coverage of the Boston Red Sox, New England Patriots, Boston Bruins, New England Revolution and a variety of local high school and colleges has expanded. Plans are in place to extend the Service’s comprehensive athletic coverage by developing a Women's Sports Medicine Program and, with the collaboration of Dr. Ross Zafonte and the Spaulding Rehabilitation Hospital, a Center for Concussion Treatment and Research (CCTR). The problem of concussions in contact sports from the Pop Warner level to the professional level is a very serious one that has not, as yet, been systematically addressed.

The Primary Care Sports Medicine Clinic has also opened in the Sports Medicine Center, and its patient referrals are growing.

The Sports Medicine Fellowship program continues to attract outstanding candidates from around the country. The Service has a number of visiting fellows and visiting residents from the United States, Europe and Japan. Broader teaching activities include the Sports Medicine 2010 Course given in collaboration with the Department of Radiology.

The Sports Medicine research program remains very productive, and has grown with its affiliation with the Biomechanical Engineering Laboratory under the direction of Dr. Guoan Li, the Tissue Engineering Laboratory with Mark Randolph, Media Laboratory at MIT along with Dr. Joseph Paradiso, Spaulding Rehabilitation Hospital in association with Dr. Ross Zafonte and the Department of Human Evolution at Harvard College in collaboration with Dr. Daniel Lieberman. Recent grants from the NFL Charities (Drs. Gill and Berkson) and the NIH (Dr. Gill and Mr. Randolph) have added substantial support to these programs. A new initiative on the use of platelet-rich plasma (PRP) has been undertaken by Drs. McInnis and Berkson. Dr. Thomas J. Gill, III, is involved with all aspects of the research program as Director of Research for the Sports Medicine Service. In the academic year 2009- 2010, the faculty of the Sports Medicine Service published 27 papers, 10 chapters and 1 review article, and published 1 book on Techniques of Knee Arthroscopy.

The Sports Medicine Service physicians have received a number of recent honors. Dr. Arthur Boland was honored with the establishment of the Arthur L. Boland Award by Harvard University for an outstanding graduating senior athlete who plans to attend medical school. Dr. Luke S. Oh received the Mel Post Award for Excellence in Clinical Research from the American Shoulder and Elbow Surgeons. Drs. Bonvaronit Chuckpaiwong, Eric Berkson and George Theodore were awarded the Nicola's Foundation Young Researchers Award of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine in Osaka, Japan.

The Sports Medicine Service and the Spaulding Rehabilitation Hospital play a major role in the study of traumatic brain injury as part of the Home Base Program of the Red Sox Foundation and the MGH to provide diagnosis, treatment and rehabilitation to veterans with traumatic brain injury and post-traumatic stress disorder.

A growing focus of the Sports Medicine Service is to treat athletic injuries, including concussions in young people and to develop sound criteria for return-to-play (parallel to our work to develop return-to-combat criteria for the military).

Congratulations to the Sports Medicine Service on all these wonderful accomplishments.

Patel Arthroscopy Laboratory

We were pleased to open the new Patel Arthroscopy Laboratory at the Sports Medicine Center in June. The Laboratory provides simulation training for residents and fellows, and we hope to expand the Laboratory’s use to trainees from other institutions. Dr. Patel pioneered the development of numerous tools and techniques for arthroscopic surgery of the knee and was one of the first individuals to develop the current forceps and shavers that are frequently utilized for this common procedure. He is viewed as one of the founding fathers of arthroscopic surgery and this learning laboratory named in his honor is a wonderful tribute to his contributions. The Sports Medicine Service also hosts groups of young students who may have an interest in medicine to visit, observe and have some hands-on experience in the Patel Arthroscopy Laboratory.

Orthopaedic Spine Service

The Orthopaedic Spine Center at the MGH is under the direction of Kirkham B. Wood, MD, and now is in its 11th year of existence. All aspects of spine care, teaching, and research are under the auspices of this Service. Our Multidisciplinary Orthopaedic Spine Center includes: Attendings, Kirkham Wood, MD; Joseph Schwab, MD; and Physiatrists: James Sarni, MD; Leonid Shinchuk, MD; and David Binder, MD. James Rathmell, MD, an anesthesiologists with the MGH Pain Center work closely with this multidisciplinary program to provide a full breadth of services to our patients.

Dr. Joseph Schwab, is a member of two services, the Orthopaedic Oncology Service and the Orthopaedic Spine Center. Dr. Schwab's work and interest is in metastatic disease of the spine, primary spine tumors, and bone and soft-tissue tumors. Dr. Schwab is integrating a highly active Orthopaedic Spine practice along with his clinical practice in Orthopaedic Oncology. Dr. Schwab recently received a Masters in Clinical Investigation from the School of Health Sciences and Technology at Harvard Medical School and MIT.

The Harvard Combined Spine Fellowship (BWH attendings, Drs. Mitchell Harris and Christopher Bono) has three fellows (2 at MGH, and 1 at BWH). The fellows are actively involved in teaching and research programs in addition to their clinical duties. The Spine Fellowship has authored papers in the Journal of Biomechanics, Spine, Journal of Spinal Disroders and Techniques, European Spine Journal, Oncology, and multiple textbook chapters.

Dr. Kirk Wood and Dr. Guoan Li, Director of the Bioengineering Laboratory, continue to collaborate actively in the area of Spine Kinematics. Dr. Wood is using the Dual-Fluoroscopic Kinematics system to better study the kinematics of the cervical and lumbar spine. Dr. Li explains, "The implication of this work is to better provide excellent kinematics data as we move into the field of disc replacement surgery." In addition, Dr. Wood has developed a spinal database along with Henrik Malchau, MD, PhD.

The Spine Biomechanics research team under Dr. Li was the recent recipient of an R-21 Investigator award from the NIH for two years as well has having received funding grants from the Scoliosis Research Society and the North American Spine Society.

RESEARCH UPDATES

Bioengineering Laboratory

The Bioengineering Laboratory under the direction of Guoan Li, PhD, celebrated another productive year. The Laboratory continues to play an active role in the field of musculoskeletal engineering and biomechanics. This year they reported the first in vivo data on dynamic tibiofemoral cartilage deformation as well as in vivo lumbar intervertebral disc deformation. The Laboratory also reported on the gender morphology of human patellofemoral joints and the corresponding kinematics. The Laboratory had several outstanding papers, including a publication in Arthritis and Rheumatism, a journal with the highest impact in Orthopedics and Rheumatology combined. It was found that rupture of the ACL alters the in vivo cartilage contact biomechanics by shifting the contact location to regions of thinner cartilage and by increasing the magnitude of the cartilage contact deformation. Other investigations evaluated the biomechanical as well as clinical performance of various contemporary ACL reconstructions including the controversial double-tunnel double-bundle technique.

The Laboratory has a fabulous contingent of outstanding graduate students from MIT, including Kartik Varadarajan, Daniel Massimini, Ali Hosseini, and Shaobai Wang and postdoctoral fellows, including Drs. Samuel Van de Velde, Michal Kozanek, Qun Xia, Bing Yue, Jong-Keun Seon, Fang Liu, Takanebu Sumino, Zongmiao Wan, Weishi Li, and Chihhui Chen. Mr. Massimini continues to conduct research on in vivo human shoulder biomechanics in collaboration with Dr. J.P. Warner and work towards his PhD degree. Mr. Hosseini, together with Drs. Kozanek and Van de Velde, continue to investigate in vivo ACL biomechanics using advanced imaging technology in collaboration with Drs. Thomas Gill, Peter Asnis and Luke Oh. Mr. Wang and Drs. Wan, Kozanek and Li are actively studying intrinsic biomechanics of human lumbar spine in collaboration with Drs. Kirkham Wood and Brian Grottkau. Drs. Varadarajan, Yue, Sumino and Liu made enormous progress in the study of human patellofemoral joint kinematics and the comparison of male and female knee morphology in collaboration with Dr. Andrew Freiberg and me. We performed a human knee morphological study by comparing the Caucasian and Asian populations.

Dr. Varadarajan received the First Award in the 2009 Annual ASME Bioengineering Conference in PhD Thesis Competition. This is a very prestigious award. Congratulations to Dr. Varadarajan on this distinct accomplishment! I look forward to his future contributions to the field.

Drs. Kozanek, Varadarajan, Bedair and Rubash have also put together a chapter on total knee arthroplasty biomechanics for the upcoming edition of Orthopaedic Knowledge Update. Drs. Samuel Van de Velde, Kozanek and Gill are actively publishing on in vivo ACL and PCL biomechanics. Dr. Van de Velde has recently been awarded the prestigious Ruth L. Kirschstein fellowship by the NIH and will soon begin his studies at the Harvard School of Public Health. Hemanth Reddy Gadikota is our core bioengineer and has actively participated in a variety of clinical and robotic projects. Mr. Gadikota, Drs. Seon, Wu and Sutton have successfully conducted a series of biomechanical testing of various ACL reconstruction techniques using the robotic system. There have also been several new additions to the Laboratory. Dr. Sumino came from Tokyo to work on improving the biomechanics of total knee arthroplasty. Dr. Chen joined us from Taiwan to investigate biomechanics of ACL reconstruction in vivo. Dr. Wan, a senior resident from Changsha, China, came aboard the spine team to help Drs. Wood and Mansfield in their investigation of biomechanics of surgical treatment of spinal stenosis.

The success of the Laboratory is measured not only by the impact of its research but also by the success of its alumni. Dr. Seon, upon his return to Korea, has continued to publish and design new studies at an impressive pace. Dr. Xia, has become the Chairman of the Department of Orthopedics in Tianjin, China and has assembled his own testing system for in vivo motion analysis of the spine. Dr. Wu has rejoined his department in Taipei, Taiwan and has been awarded the prestigious Travelling Fellowship by the Orthopaedic Research Society. Dr. Passias has joined the spine service at the Hospital for Special Surgery for his clinical fellowship and continues to publish and conduct studies despite his demanding clinical commitments. Dr. Varadarajan defended his PhD thesis at MIT and will stay in the Bioengineering Laboratory at the MGH as a research scientist. We are very proud of them and wish them all the best in their careers!

Finally, this year at the ORS/AAOS meeting, the team had over 30 talks, podium presentations, and posters. They published over a dozen publications in various peer review journals in the areas of arthroplasty, sports medicine, spine, foot and ankle, as well as bioengineering. Wow!!! What a year!

The Shoulder Research Laboratory under the direction of JP Warner, MD, had a great year with the adoption of a dedicated research space. Since then, progress within the Laboratory has occurred at an exponential rate. This year they reported the first data on in vivo glenohumeral contact kinematics after total shoulder arthroplasty in the Journal of Bone and Joint Surgery. It was found that contact kinematics are not centered on the glenoid as traditionally thought, but in fact are mostly superior posterior. These data have huge implications for the next generation design of shoulder arthroplasty. The Laboratory also developed a technique for nerve tagging for analysis by dual plane fluoroscopy in a cadaver model. The suprascapular nerve was tracked under simulated rotator cuff forces. It was found that a tear of the supraspinatus and infraspinatus caused a retraction of the nerve towards the spinoglenoid notch and may be responsible for neuropathy common in many rotator cuff patients.

Luke Oh, MD, a recent addition to the Department won an AEF grant to investigate the in-vivo kinematics of the shoulder in patients with anterior instability treated with the Latarjet technique. Daniel Massimini, a PhD candidate, in the Department of Mechanical Engineering at MIT supervises all research activities within the Laboratory. Mr. Massimini focuses his research efforts on in vivo shoulder biomechanics. Mr. Massimini just began a new study to quantify the coupled scapular and humeral contributions to dynamic shoulder motion in healthy individuals during the activities of daily living. These data will serve as a benchmark for all future studies of the kinematics of the shoulder. Dr. Warner is passionate about our shoulder research and has an endless supply of questions to answer. The Shoulder Research Laboratory is looking forward to another productive year. Plans are in the works to add a full time research engineer and postdoctoral fellow.

Harris Orthopaedic Laboratories

The Harris Orthopaedic Laboratory (HOL) is under the co-direction of Orhun Muratoglu, PhD, and Henrik Malchau, MD, PhD. Members of the HOL have contributed to the field of Adult Reconstructive Surgery for over four decades. A variety of different topics have been studied and major contributions have been made particularly in the area of implant stability, implant fixation, bearing-surface applications, and 1st, 2nd and now 3rd generation of highly crosslinked polyethylenes. Currently, there are a number of outstanding clinical projects underway at the HOL.

Charles Bragdon, PhD, is leading a study to evaluate the clinical performance of first generation highly cross-linked polyethylene and the vitamin-E doped irradiated polyethylenes for use in hip and knee arthroplasties. Dr. Bragdon has been in the laboratory for over two decades. Charlie and I did the first uncemented titanium fiber metal canine hip replacements in the mid-eighties! An additional clinical outcomes study in its 7th year utilizes RSA techniques to determine the wear behavior of crosslinked polyethylene in conjunction with the traditional as well as large femoral heads. This study has shown marked reduction in wear and femoral head penetration at the 7th year benchmarks. Dr. Malchau and co-investigators are quite pleased with these results and state, "So far the first generation highly crosslinked polyethylene performs as predicted in the preclinical experiments and seems to be the bearing of choice in the active patient."

The HOL is also focusing on materials including crosslinked polyethylene with low-wear and high strength for applications in hip, knee and other joint arthroplasties. This section of the HOL is under the direction of the Orhun Muratoglu, PhD, an innovator in this field for over 15 years. The newest technology utilizes Vitamin E to stabilize the residual free radicals and to protect the base polymer against oxidation. FDA cleared the use of this material in total hips in 2007 and for total knees in 2008. Ebru Oral, PhD, and a group of scientists along with Dr. Muratoglu are leading this important area of investigation.

A new exciting innovation is also in the area of load bearing materials for use in total joint reconstruction. This new technology limits the crosslinking of the polyethylene to the articular surface layer, where it is needed to improve wear resistance. This method minimizes the loss of mechanical properties. The investigators at the HOL think that this new technology will be suitable for younger and more active patients.

New exciting areas of collaboration include the area of knee wear. Drs. Orhun Muratoglu, Henrik Malchau, Harry Rubash, and Guoan Li, are continuing to tackle the difficult and perplexing problem of knee wear. This project will provide some exciting information with the ultimate goal of detecting in-vivo wear as it relates to implant longevity. Dr. Li states, "The innovative dual fluoroscopic technique in a combined effort with the HOL, is being developed to detect in-vivo poly wear to predict longevity of patients after TKA."

Another new area of collaboration for the HOL is in the area of spine kinematics and spine reconstruction. The team is working on technology using hydrogels as materials for intervetebral disc replacement along with biodegradable polymer technology. These studies could benefit many of our patients with degenerative axial-skeleton disease as well as spinal deformity. Dr. Kirkham Wood reports, "Ongoing studies in the Biomechanics Lab include projects studying the three-dimensional analysis of intervertebral disc motion using a combined MRI-fluoroscopic technique; the effects of disc degeneration on in-vivo disc deformation and the effect of spinal deformity surgery on adjacent segment vertebral kinematics using noninvasive techniques."

The HOL is a source of enormous activity and energy in the area of translational and basic science research. The skillful scientists in this laboratory had another incredible year at the ORS and the AAOS with over 20 abstracts presented. Once again the members of this outstanding Laboratory have added a tremendous amount of new knowledge to our field; and the first generation highly crosslinked UHMWPE developed in this laboratory has now been implanted in over two million hip and knee patients worldwide. I know that these important contributions will continue in the future. Again, another fabulous year!!!

Laboratory of Musculoskeletal Engineering

The Laboratory for Musculoskeletal Tissue Engineering, under the direction of Mr. Mark Randolph and Thomas Gill, IV, MD, focuses on cartilage repair and regeneration in the knee. The group focuses on developing new hydrogels for articular cartilage repair and regeneration. Working with Drs. Robert Redmond and Irene Kochevar from the Wellman Center of Photomedicine, they have developed a novel means to photocrosslink collagen gel for use as an encapsulation gel for chondrocytes and neocartilage formation. Initial work on cell survival following photopolymerization was published in Tissue Engineering in 2007 (Ibusuki S et al, 13(8):1995-2001). Follow up studies on the capacity of these photopolymerized collagen gels to form neocartilage was published in the Journal of Knee Surgery in January 2009 (Ibusuki S et al 22(1):72-81). A grant from the AO Foundation is allowing for continued work with Dr. Redmond where the focus will be on improving the biomechanics of the gel and improving cell survival. A grant has recently been received from the Department of Defense to test the use of cophondrocytes encapsulated in photopolymerized collagen and PEG gels in swine to restore the articular joint surface. Parallel work on the cartilage formation capacity of human articular chondrocytes placed in hydrogels has been funded by a grant to Dr. Gill from the NFL Charities. The collaboration will also include Dr. Seemantini Nadkarni from the Wellman Center for Photomedicine who will focus on using laser speckle imaging as a noninvasive means for measuring the modulus of native and engineered cartilage.

New studies in collaboration with Dr. Orhun Muratoglu in the Department’s Harris Orthopaedic Laboratories are exploring a hybrid scaffold composed of nondegradable poly (vinyl alcohol) scaffold combined with chondrocytes for joint cartilage replacement. Several types of PVA hydrogels have been tested for cell compatibility and cartilage formation in mice with support through the Academic Enrichment Fund grant from the Department of Orthopedic Surgery. Progress to date has identified several candidate gels that support new cartilage formation and one recent publication describes the use of this PVA gel for craniofacial purposes (Bichara DA et al J Surg Res. 2010 Apr 24).

Previous work funded by the AO Foundation focused on tissue engineering strategies to repair lesions in the avascular regions of the meniscus. The results demonstrated an efficient means to seed chondrocytes onto polygalactin (PLGA) scaffolds, and the capacity of this cell-scaffold constructs to heal bucket handle lesions made in swine menisci. One study published in the American Journal of Sports Medicine in November 2006 (Weinand C, et al, 2006, 11:34) presented preliminary data on using allogeneic chondrocytes for meniscal repair. Recent work funded by the Musculoskeletal Transplant Foundation has allowed for testing the utility of allogeneic chondrocytes for healing lesions in the swine meniscus. This work is nearing completion and will demonstrate the contribution of the allogeneic cells to the repair as well as document the host's immune response to the allogeneic cells. Impressive work and an impressive year!

Sarcoma and Molecular Biology Laboratory

The Sarcoma Molecular Biology Laboratory (SMBL), is under the direction of Zhenfeng Duan, MD, PhD and Orthopaedic Oncology Service Chief, Francis J. Hornicek, MD, PhD. The focus of the Laboratory's work is to examine the mechanisms of multidrug resistance, to identify small molecules and targets to reverse drug resistance and to understand the characterization of molecular mechanisms governing growth, and the proliferation of human sarcoma cells.

The overall objectives of the Laboratory are to explore biological mechanisms of tumors arising in bone and other tissues. One of the major focuses is to elucidate the mechanisms of the development of drug resistance in cancer. Previously, Drs. Hornicek and Duan have found multidrug resistance could be partially reversed by siRNA targeting of ABCB1 (MDR1) or by combination of nanoparticles with chemotherapy drug. Recently, they identified two small molecules that can overcome drug resistance in vitro. Another significant aim of the research is to define the essential kinases that are responsible for proliferation and survival of human sarcoma cells. In addition, translational research into new treatment options for sarcoma patients has been undertaken.

Continued collaboration with other institutions and pharmaceutical companies has provided the foundation for evaluation of new drug development. Many of these drugs are derived from marine sources and their corresponding biochemical structures are quite complex. The Sarcoma Molecular Biology Laboratory has published articles pertaining to multiple drug resistance in human cancer. Research projects on sarcoma biology have received funding from a variety of sources including NIH, foundations, corporate sponsors, and benefactors.

The Sarcoma Research Group at the MGH includes investigators from multiple disciplines, as does the clinical group. I look forward to the results of the Laboratory continued research expansion and to see the efforts of their further collaboration within the Harvard community.

Laboratory for Musculoskeletal Research and Innovation (LMRI )

The focus of the newly created Laboratory for Musculoskeletal Research and Innovation (LMRI) under the direction of S. Adam Hacking, PhD is to provide innovative solutions for unmet clinical needs in orthopedics.

Dr. Hacking reports that he is actively recruiting students and research fellows. Dr. Wang MD, PhD will join the lab this fall and Dr. Ari Salmi, PhD will join the Laboratory this spring. Ongoing Laboratory projects include bone and vascular tissue engineering, enhancement of fracture healing and implant fixation, the development of novel surfaces to reduce implant infection and the use of noninvasive techniques to quantify implant stability.

Dr. Hacking looks forward to working closely with the surgical staff to develop and refine new technology. The Laboratory is adept with large and small animal models, techniques for undecalcified histology, testing instrumentation, micro-CT imaging, design and fabrication and mechanical testing. Collaborations exist with local researchers (Harvard, MIT and U of Helsinki) that broaden and compliment the capabilities of the laboratory. To visit the lab, please stop by GRJ 1120 or email ahacking@partners.org. Dr. Hacking congratulations on your new laboratory and welcome to our Department!

DEPARTMENT HOLIDAY PARTY

In December we celebrated the holiday season with our annual black tie Orthopaedic Department Holiday Party. This increasingly popular event was again a resounding success. We returned to the beautiful Seaport Hotel in South Boston where over 600 guests in attendance were treated to festive music, holiday-themed decor, and an absolutely wondrous buffet dinner. Plans are already underway for the 2010 party at the Seaport Hotel for this "not to be missed holiday event."

PERSONAL NOTE

It is a great pleasure and a distinct honor to work with all of you in this fabulous Department. I'm pleased to report that our Department has been recognized again as one of the top in the nation....# 3 out of nearly 1600 hospitals by U.S. News and World Report! You can view the rankings at: http://health. usnews.com/best-hospitals/rankings/orthopedics. The MGH as a whole was rated #3 out of the 152 hospitals that made it into the new 2010-11 Best Hospitals rankings (out of nearly 5,000 that were considered). I would like to thank each of you for your continued outstanding efforts for our patients and our profession. Well done!!!

My family has had a lot to celebrate over the past year. Kim and I were extremely proud when our oldest, Brad, graduated from Rollins College. Steve will be entering his senior year at Boston University in the fall and we will be having another graduation next year. Krissy is a rising junior at Rollins College. She is an economics major with an interest in business administration. Krissy and her horse, Quizz d'Orange, recently placed 1st at the 2-Day (Dressage, Cross Country and Stadium Jumping) Huntington Farm Horse Show. Our family gathered together in July to celebrate my mother-in-law's 90th birthday. What a milestone! Congratulations Mary Ertman-Kindler. Kim had the opportunity to spend several months in Florida this past winter and enjoyed the extra time she had with Brad and Krissy.

I wish you all the best of success in the Department and I stand by to assist you.





OJHMS Home • Instructions to Authors • Letter from the Editor • Advertisers Info • Dedication • Manuscripts


The Orthopaedic Journal at Harvard Medical School is an annual publication
of the Harvard Combined Orthopaedic Residency Program. Copies are distributed
free of charge and the entire volume can be viewed here on our website.

To add your name to our mailing list and for any other correspondence please contact us at:

The Orthopaedic Journal at Harvard Medical School
Massachusetts General Hospital, White 535,     55 Fruit Street, Boston, MA 02114
e-mail: ojhms@partners.org    •    phone: 617-726-2942    •    fax: 617-726-3124

Copyright © Orthopaedic Journal at Harvard Medical School. All rights reserved.

Hosted by: Web Results Inc.